Prolotherapy is derived from the word "prolo" which indicates "proliferation" or "causing proliferation" (growth). It indicates the growth or formation of new ligamnets, tissues, etc. in areas that are lax or have been injured. This is accomplished through the natural production of collagen and cartilage. This newly formed collagen is integral in strengthening and restoring joints.
Prolotherapy is helpful not only when there is damage through trauma, but also when there is abnormal wear and stretching, as well as when the healing process did not progress to proper completion (as sometimes occurs when the immune system is weak or when anti-inflammatory medications were used).